Motif ID: FOX{C1,C2}.p2

Z-value: 0.876


Transcription factors associated with FOX{C1,C2}.p2:

Gene SymbolEntrez IDGene Name
FOXC1 2296 forkhead box C1
FOXC2 2303 forkhead box C2 (MFH-1, mesenchyme forkhead 1)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
FOXC1chr6_+_1556543-0.155.9e-01Click!
FOXC2chr16_+_851583570.146.0e-01Click!


Activity profile for motif FOX{C1,C2}.p2.

activity profile for motif FOX{C1,C2}.p2


Sorted Z-values histogram for motif FOX{C1,C2}.p2

Sorted Z-values for motif FOX{C1,C2}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOX{C1,C2}.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_-_115826481 2.306 NM_001164346
 ZBTB20
zinc finger and BTB domain containing 20
chr17_-_61655915 1.596 NM_000042
 APOH
apolipoprotein H (beta-2-glycoprotein I)
chr4_+_74491272 1.548 ALB
albumin
chr14_-_93988838 1.318 NM_001080451
 SERPINA11
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 11
chr10_+_7785347 1.144 ITIH2
inter-alpha (globulin) inhibitor H2
chr10_+_7785360 1.064 ITIH2
inter-alpha (globulin) inhibitor H2
chr2_-_216008689 1.030 FN1
fibronectin 1
chr10_+_7785331 1.012 ITIH2
inter-alpha (globulin) inhibitor H2
chr10_+_7785290 0.995 ITIH2
inter-alpha (globulin) inhibitor H2
chr14_+_94117511 0.986 SERPINA5
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
chr4_+_186368277 0.959 NM_031953
 SNX25
sorting nexin 25
chr3_-_150578023 0.956 TM4SF1
transmembrane 4 L six family member 1
chr4_+_74500748 0.885 ALB
albumin
chr3_-_150578103 0.850 TM4SF1
transmembrane 4 L six family member 1
chr14_+_94117483 0.835 NM_000624
 SERPINA5
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
chr12_+_99391870 0.833 NR1H4
nuclear receptor subfamily 1, group H, member 4
chr10_+_7785235 0.817 NM_002216
 ITIH2
inter-alpha (globulin) inhibitor H2
chr4_-_100359353 0.806 NM_000672
NM_001102470
 ADH6

alcohol dehydrogenase 6 (class V)

chr6_+_158358067 0.795 NM_001178088
 SYNJ2
synaptojanin 2
chr1_+_111573855 0.786 NM_001025199
 CHI3L2
chitinase 3-like 2

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
6.16 2.09e-02 GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation

Gene overrepresentation in compartment category:

Showing 1 to 6 of 6 entries
enrichment   p-value GO term description
5.89 4.17e-02 GO:0031983 vesicle lumen
2.55 2.32e-02 GO:0031012 extracellular matrix
1.84 3.26e-02 GO:0044421 extracellular region part
1.54 4.89e-02 GO:0005576 extracellular region
1.44 7.36e-04 GO:0071944 cell periphery
1.41 4.57e-03 GO:0005886 plasma membrane

Gene overrepresentation in function category:

Showing 1 to 6 of 6 entries
enrichment   p-value GO term description
19.45 1.02e-02 GO:0016175 superoxide-generating NADPH oxidase activity
2.10 4.10e-02 GO:0005509 calcium ion binding
1.80 1.63e-02 GO:0004888 transmembrane receptor activity
1.71 6.87e-03 GO:0004872 receptor activity
1.58 2.47e-02 GO:0004871 signal transducer activity
1.58 2.47e-02 GO:0060089 molecular transducer activity